Opioid receptor antagonist (PAMORA) (Formulary: GI)

Important: Formulation and dosage details

Formulation:

Film-coated tablets 12·5mg, 25mg (Restricted: Specialist recommendation only)

Dosage:

As per SMC 1106/15: the treatment of opioid-induced constipation in adult patients who have had an inadequate response to laxative(s).

Important: Formulation and dosage details

Formulation:

Film-coated tablets 200 microgram (Restricted: Specialist recommendation only)

Dosage:

As per SMC2242: For the treatment of opioid induced constipation (OIC) in adult patients who have previously been treated with a laxative.

Place in therapy:

To be considered if naloxegol is not available.