| Drug | Amendment | Date formulary amended | Ratification date |
| October 2023 | |||
| Cenobamate tablets SMC2408 | Addition | 31/10/23 | 26/10/23 |
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NHS Highland
Formulary updates (Formularies)
| DRUG | REASON FOR DELETION | SUBGROUP MEETING |
| Acetic acid spray 2% | discontinued | August 2019 |
| Aciclovir eye ointment 3% (Zovirax®) | discontinued | January 2019 |
| Alphosyl shampoo | discontinued | February 2023 |
| Alprostadil 250 microgram urethral application (MUSE®) | discontinued | April 2020 |
| Betamethasone 0.1% eye ointment | discontinued | April 2020 |
| Biphasic Isophane insulin Injection 25% soluble, 75% isophane 100 units/mL 3mL cartridge (Insuman® Comb 25 for ClikSTAR®, Autopen®) and 3mL pre-filled pen (Insuman Comb 25 SoloStar®) | discontinued | February 2023 |
| Biphasic Isophane insulin Injection 50% soluble, 50% isophane 100 units/mL and 3mL cartridge (Insuman® Comb 50 for ClikSTAR®, Autopen®) | discontinued | February 2023 |
| Calcium syrup (calcium 2·5mmol or 102mg/5mL) unlicensed | discontinued | October 2022 |
| Cervarix vaccine suspension for injection 0.5ml pre-filled syringes | discontinued | June 2021 |
| Ciprofloxacin 3mg/mL, dexamethasone 1mg/mL (Cilodex) ear drops | discontinued | April 2021 |
| Clozapine oral suspension 50mg/ml | Formulary review; use 25mg and 100mg orodisperisble tablets | April 2022 |
| Collagenase | discontinued | December 2020 |
| Cyclo-progynova 2mg tablets | discontinued | April 2020 |
| Daclatasvir 30mg and 60mg tablets | discontinued | November 2019 |
| Dasabuvir 250mg tablets | discontinued | February 2021 |
| Deferiprone 500mg tablets | discontinued | November 2019 |
| Dermamist 10% spray | discontinued | October 2022 |
| Desflurane Inhalation vapour 1mL/1mL | No longer used | February 2022 |
| Dexamethasone soluble tablets 2mg, 4mg, 8mg | Formulary review; standard tablets can be dispersed in water | December 2021 |
| Diazepam rectal solution tubes 2.5mg/1.25mL | removed due to unavailability | December 2021 |
| Dicobalt Edetate 300mg/20mL injection | discontinued - replaced with Sodium nitrite solution for injection | May 2020 |
| Dihydrocodeine 10mg/5ml oral solution | discontinued | February 2021 |
| Diprobase cream and ointment | Formulary review; Zeroderma range first line choice | February 2021 |
| Dithranol (Dithrocream) 2% cream | discontinued | April 2021 |
| Dithranol (Dithrocream®) 0.25%, 0.5% and 1% cream | discontinued | April 2022 |
| Doublebase® Gel | replaced with Zerodouble® Emollient Gel | January 2019 |
| Engerix B 20microgram/1mL | discontinued | April 2021 |
| Enzalutamide 40mg capsules | discontinued - replaced with enzalutamide tablets | April 2020 |
| Epaderm ointment | Formulary review, Zeroderma range first line choice | February 2021 |
| Estradiol (Vagifem) | Vagirux preferred brand for environmental reasons | October 2021 |
|
Ethinylestradiol and norethisterone (Loestrin) 20 and 30 tablets |
discontinued | October 2019 |
|
Exenatide modified release powder for reconstitution 2mg/pre-filled pen |
discontinued - use prolonged-release suspension for injection 2mg/pre-filled pens | October 2022 |
| Flecainide 200mg modified release tablets | discontinued | April 2020 |
| Fluphenazine decanoate solution for injection (oily) 12∙5mg/0∙5mL, 25mg/1mL, 100mg/1mL |
discontinued |
August 2021 |
| Fluticasone propionate/formoterol 125 microgram/5 microgram (Flutiform® K-haler®) |
discontinued |
April 2021 |
| Gynest 0.01% estriol |
Formulary review, estriol cream of choice: estriol 0.1% |
August 2020 |
| Haloperidol 500 microgram capsules | discontinued | April 2020 |
| Human papillomavirus (type 16, 18) vaccine (absorbed) suspension for injection 0.5ml pre-filled syringes | discontinued | June 2021 |
| Hydrocortisone 10% rectal foam | discontinued | April 2020 |
| Hydrocortisone (as acetate) (aqueous suspension) 25mg/1mL injection | discontinued | April 2022 |
| Ibandronic acid infusion 2mg/2mL and 6mg/6mL | no longer used for malignant disease | May 2019 |
| Infliximab powder for concentrate for solution for infusion 100mg (Remicade®) | Formulary review, Remsima should be used | June 2021 |
| Infliximab powder for concentrate for solution for infusion 100mg | Formulary review, Inflectra, Remsima and Zessly brands should be used | April 2022 |
| Insuman Comb 25 100units/ml suspension for injection 5ml vials | discontinued | June 2021 |
| Insulin glargine injection 100 units/mL 3mL cartridge (Abasaglar® for Autopen®) and (Lantus for ClikSTAR, Autopen®24) | discontinued | February 2023 |
| Isophane insulin 100 units/mL 5mL vial (Insuman® Basal) injection | discontinued | April 2022 |
|
Isophane insulin 10mL vial (Insulatard®), removed 3mL cartridge (Insuman® Basal for ClikSTAR, Autopen®), (Humulin I® for Autopen®) and 3mL pre-filled pen (Insuman Basal SoloStar®) |
discontinued | February 2023 |
| Isoprenalin injection 2mg/2mL unlicensed (hospital use only) | Use licensed version | April 2022 |
| Macrogol 3350 with potassium chloride, sodium bicarbonate and sodium chloride (Klean-Prep) oral powder 69g/sachet | Formulary review, VistaPrep should be used | October 2021 |
| Magnesium hydroxide Mixture BP | alternative products available | December 2020 |
| Mannitol (Viaflex®) | discontinued | August 2019 |
| Mesalazine 400mg and 800mg (Asacol® brand only) | May 2019 | |
| Mesalazine foam enema (Asacol®) | discontinued | October 2021 |
| Methotrexate subcutaneous all strengths (Zlatal® brand only) | Formulary review; Methofill should be used | December 2020 |
| Nepafenac 1mg/ml eye drops | Replaced by nepafenac 3mg/ml eye drops | June 2021 |
| Norethisterone acetate and ethinylestradiol (Loestrin®) | discontinued | November 2019 |
| Ofatumumab concentrate for solution for infusion 20mg/mL | discontinued | February 2021 |
| Orlistat capsules | No longer recommended by NHS Highland. See the NHS Highland Adult Healthy Weight pathway. | January 2019 |
| Pembrolizumab 50mg powder for infusion | discontinued | June 2022 |
| Pirfenidone 267mg capsules | discontinued - use tablets. | June 2022 |
| Prazosin 1mg tablets | discontinued | April 2022 |
| Prednisolone retention enema 20mg/100mL | discontinued | August 2019 |
|
Prednisolone foam enema 20mg/metered application (as metasulfobenzoate sodium) |
Formulary review, budesonide rectal foam 2mg/dose should be used | February 2022 |
| Ranitidine 75mg/5ml oral solution sugar free | discontinued | June 2021 |
| Ranitidine 150mg and 300mg effervescent tablets | discontinued | June 2021 |
| Ranitidine 150mg and 300mg tablets | discontinued | February 2022 |
| Selegeline oral lyophilisate tablet 1.25mg | discontinued | December 2020 |
| Simeprevir capsules 150mg | discontinued | February 2021 |
| Sitagliptin 25mg, 50mg and 100mg tablets | replaced with alogliptin | August 2019 |
| Sodium aurothiomalate 10mg/0∙5ml and 50mg/0∙5ml injection | discontinued | August 2021 |
| Sodium chloride 4∙5% eye drops | discontinued - replaced by sodium chloride 5% preservative free eye drops | August 2021 |
| Somatropin (Norditropin Simplexx®) 5mg/1∙5ml, 10mg/1∙5ml and 15mg/1∙5ml solution for injection | replaced with Norditropin Flexpro | August 2021 |
| Theophylline (Slo-Phyllin®) 60mg, 125mg and 250mg | discontinued | February 2020 |
| Tolterodine 1mg and 2mg tablets and 4mg modified release | replaced with solifenacin | April 2020 |
| Triamcinolone acetonide 10mg/1ml suspension for injection ampoules | discontinued | February 2021 |
| Ulipristal acetate (Esmya) 5mg tablets | discontinued | April 2021 |
| Varenicline tablets 500 microgram, 1mg, starter pack | discontinued | October 2022 |
| Viekirax 12.5mg, 50mg and 75mg tablets | discontinued | February 2021 |
| VitA-POS eye ointment preservative free | discontinued - replaced with Hylo Night | August 2021 |
| Xerotin® oral spray | not available | January 2019 |
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