Immune-related Adverse Events Management WoSCAN (550)

Scope – This guidance refers to management of immune-related adverse events caused
directly by immunotherapy. Immune-related adverse events can affect any organ system,
however, the most common adverse reactions include:

 Immune-related pulmonary toxicities
 Immune-related colitis
 Immune-related hepatitis
 Immune-related nephritis or renal dysfunction
 Immune-related endocrinopathies
 Immune-related skin toxicities
 Immune-related fatigue (new)
 Immune-related cardiovascular toxicities
 Immune-related rheumatic events
 Immune-related neurological complications
 Immune-related ophthalmological complications (new)

The aim of this guidance is to help ensure that all those involved in the delivery of
immunotherapy within the West of Scotland Cancer Network (WoSCAN) have the appropriate
knowledge and resources to deliver these treatments safely through the provision of treatment
algorithms for toxicity management.